binding of naproxen to serum proteins in patients with liver cirrhosis and healthy individuals
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abstract
a three-fold decrease of the in vitro ability of serum proteins to bind naproxen was shown in patients with cirrhosis of the liver compared to healthy individuals. this decrease was caused by quantitative changes in serum proteins in the sera of patients with liver damage. lower doses of naproxen are therefore suggested in the treatment of patients with liver dysfunction.
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Journal title:
medical journal of islamic republic of iranجلد ۹، شماره ۳، صفحات ۲۱۷-۲۱۹
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